2-Mercaptoethanol Acts as a Potentiating Factor of Interleukin-2-Dependent Lymphocyte Proliferation
نویسندگان
چکیده
منابع مشابه
Lacrimal gland-derived lymphocyte proliferation potentiating factor.
PURPOSE To determine whether lacrimal gland acinar cells are involved in modulating local immune response; to isolate and characterize a lacrimal gland factor that exerts biological activities on T lymphocytes. METHODS A protein factor has been purified from lacrimal gland extracts by a combination of ion exchange and gel-filtration chromatography. This factor has the capacity to enhance prol...
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Mouse spleen cells which have been depleted of adherent cells do not respond to allogeneic lymphocytes in vitro. Their cytotoxic response can be restored by inclusion of mercaptoethanol in the medium. Mercaptoethanol is shown to have a stimulatory effect also on the response of normal (unseparated) spleen cells to alloantigens. The enhancement of the DNA-synthetic and cytotoxic response is simi...
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ژورنال
عنوان ژورنال: Microbiology and Immunology
سال: 1987
ISSN: 0385-5600
DOI: 10.1111/j.1348-0421.1987.tb03130.x